Anti-Ago1 antibody [OTI4G1],Abcam,AB279392

Host

Mouse

Reactivity

Human

Application

WB, IHC-P

Platform ID

BAB960029753

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Ago1 antibody [OTI4G1]
Cat. No.AB279392
HostMouse
IsotypeIgG1
ReactivityHuman
ApplicationWB, IHC-P
ClonalityMonoclonal
Clone NumberOTI4G1
Concentration1 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human AGO1 aa 200-500. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A/G
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.3 Preservative: 0.02% Sodium azide Constituents: 50% Glycerol (glycerin, glycerine), 1% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) or short interfering RNAs (siRNAs), and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. Also required for transcriptional gene silencing (TGS) of promoter regions which are complementary to bound short antigene RNAs (agRNAs). See full target information AGO1

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