Anti-Apolipoprotein CIII antibody,Abcam,AB21032

What is this antibody validated in? Anti-Apolipoprotein CIII antibody (ab21032) is a rabbit polyclonal antibody and is validated for use in Western Blot (WB), Immunocytochemistry/immunofluorescence (ICC/IF), ELISA in Human, Monkey samples. What is the molecular weight of Apolipoprotein CIII? Anti-Apolipoprotein CIII (ab21032) specifically detects a band for Apolipoprotein CIII (UniProt: P02656) at a molecular weight of 11kDa.

Host

Rabbit

Reactivity

Human, Monkey

Application

WB, sELISA, ELISA, ICC/IF

Platform ID

BAB338904128

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Apolipoprotein CIII antibody
Cat. No.AB21032
HostRabbit
IsotypeIgG
ReactivityHuman, Monkey
ApplicationWB, sELISA, ELISA, ICC/IF
ClonalityPolyclonal
Concentration1 mg/mL Batch dependent concentration
ImmunogenFull Length Protein corresponding to Human Apolipoprotein C-III. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.02% Sodium azide Constituents: PBS, 0.435% Sodium chloride, 0.0292% EDTA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Component of triglyceride-rich very low density lipoproteins (VLDL) and high density lipoproteins (HDL) in plasma (PubMed : 18201179, PubMed : 22510806). Plays a multifaceted role in triglyceride homeostasis (PubMed : 18201179, PubMed : 22510806). Intracellularly, promotes hepatic very low density lipoprotein 1 (VLDL1) assembly and secretion; extracellularly, attenuates hydrolysis and clearance of triglyceride-rich lipoproteins (TRLs) (PubMed : 18201179, PubMed : 22510806). Impairs the lipolysis of TRLs by inhibiting lipoprotein lipase and the hepatic uptake of TRLs by remnant receptors (PubMed : 18201179, PubMed : 22510806). Formed of several curved helices connected via semiflexible hinges, so that it can wrap tightly around the curved micelle surface and easily adapt to the different diameters of its natural binding partners (PubMed : 18408013). See full target information Apolipoprotein C-III

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