Anti-Aquaporin 1 antibody [1/22],Abcam,AB9566

What is this antibody validated in? Anti-Aquaporin 1 antibody [1/22] (ab9566) is a mouse monoclonal antibody and is validated for use in Western Blot (WB), Flow Cytometry (Flow Cyt), Immunohistochemistry (IHC-P) in Human, Rat samples. What is the molecular weight of Aquaporin 1? Anti-Aquaporin 1 [1/22] (ab9566) specifically detects a band for Aquaporin 1 (UniProt: P29972) at a molecular weight of 29kDa. Trusted by the scientific community Anti-Aquaporin 1 [1/22] (ab9566) was first used in a scientific publication in 2002 and has been cited over 60 times in peer-reviewed journals. Reviewed by scientists Anti-Aquaporin 1 [1/22] (ab9566) has over 15 independent reviews from customers.

Host

Mouse

Reactivity

Rat, Human

Application

Flow Cyt, WB, IHC-P

Platform ID

BAB776872653

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-Aquaporin 1 antibody [1/22]
Cat. No.AB9566
HostMouse
IsotypeIgG2b
ReactivityRat, Human
ApplicationFlow Cyt, WB, IHC-P
ClonalityMonoclonal
Clone Number1/22
Concentration1 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Human AQP1 aa 200 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.097% Sodium azide Constituents: PBS, 0.2% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Forms a water channel that facilitates the transport of water across cell membranes, playing a crucial role in water homeostasis in various tissues (PubMed : 1373524, PubMed : 23219802). Could also be permeable to small solutes including hydrogen peroxide, glycerol and gases such as amonnia (NH3), nitric oxide (NO) and carbon dioxide (CO2) (PubMed : 16682607, PubMed : 17012249, PubMed : 19273840, PubMed : 33028705, PubMed : 8584435). Recruited to the ankyrin-1 complex, a multiprotein complex of the erythrocyte membrane, it could be part of a CO2 metabolon, linking facilitated diffusion of CO2 across the membrane, anion exchange of Cl(-)/HCO3(-) and interconversion of dissolved CO2 and carbonic acid in the cytosol (PubMed : 17012249, PubMed : 35835865). In vitro, it shows non-selective gated cation channel activity and may be permeable to cations like K(+) and Na(+) in vivo (PubMed : 36949749, PubMed : 8703053). See full target information AQP1

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