Anti-Aquaporin 5 antibody,Abcam,AB78486

What is this antibody validated in? Anti-Aquaporin 5 antibody (ab78486) is a rabbit polyclonal antibody and is validated for use in Western Blot (WB), Immunohistochemistry (IHC-P) in Mouse, Rat samples. What is the molecular weight of Aquaporin 5? Anti-Aquaporin 5 (ab78486) specifically detects a band for Aquaporin 5 (UniProt: P55064) at a molecular weight of 24kDa. Trusted by the scientific community Anti-Aquaporin 5 (ab78486) was first used in a scientific publication in 2009 and has been cited over 70 times in peer-reviewed journals. Reviewed by scientists Anti-Aquaporin 5 (ab78486) has over 5 independent reviews from customers.

Host

Rabbit

Reactivity

Mouse, Rat

Application

WB, IHC-P

Platform ID

BAB402085051

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Aquaporin 5 antibody
Cat. No.AB78486
HostRabbit
IsotypeIgG
ReactivityMouse, Rat
ApplicationWB, IHC-P
ClonalityPolyclonal
Concentration1 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Rat Aqp5. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.05% Sodium azide Constituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Aquaporins form homotetrameric transmembrane channels, with each monomer independently mediating water transport across the plasma membrane along its osmotic gradient (By similarity). Plays an important role in fluid secretion in salivary glands (PubMed : 10400615, PubMed : 16571723, PubMed : 18027168). Required for TRPV4 activation by hypotonicity. Together with TRPV4, controls regulatory volume decrease in salivary epithelial cells (PubMed : 16571723). Seems to play a redundant role in water transport in the eye, lung and in sweat glands (PubMed : 10619865, PubMed : 12042359, PubMed : 18027168). See full target information Aqp5

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