Anti-Aquaporin 7 antibody,Abcam,AB15123

Host

Chicken

Reactivity

Rat

Application

WB, ICC/IF, ELISA

Platform ID

BAB589628780

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Aquaporin 7 antibody
Cat. No.AB15123
HostChicken
IsotypeIgY
ReactivityRat
ApplicationWB, ICC/IF, ELISA
ClonalityPolyclonal
ImmunogenSynthetic Peptide within Rat Aquaporin-7. The exact immunogen used to generate this antibody is proprietary information.
ShippingBlue Ice
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Aquaglyceroporins form homotetrameric transmembrane channels, with each monomer independently mediating glycerol and water transport across the plasma membrane along their osmotic gradient. Could also be permeable to urea (PubMed : 9252401). Mediates the efflux of glycerol, formed upon triglyceride hydrolysis, to avoid its accumulation in adipocytes and to make it available to other tissues. In the kidney, mediates the reabsorption of glycerol, preventing its loss in urine, again participating to energy homeostasis. In pancreatic beta cells, it also mediates the efflux of glycerol, regulating its intracellular levels (By similarity). See full target information Aquaporin-7

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