Anti-Asialoglycoprotein Receptor 1/HL-1 antibody,Abcam,AB127896

Host

Rabbit

Reactivity

Mouse, Human

Application

ICC/IF, WB

Platform ID

BAB279221525

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Asialoglycoprotein Receptor 1/HL-1 antibody
Cat. No.AB127896
HostRabbit
IsotypeIgG
ReactivityMouse, Human
ApplicationICC/IF, WB
ClonalityPolyclonal
Concentration0.3 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human ASGR1 aa 1-250. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7 Preservative: 0.025% Proclin 300 Constituents: PBS, 20% Glycerol (glycerin, glycerine), 1% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface. See full target information ASGR1

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