Anti-Ataxin 1 antibody [N76/8],Abcam,AB186265

The clone number has been updated from S76-8 to N76/8, both clone numbers name the same antibody clone.

Host

Mouse

Reactivity

Human

Application

ICC/IF, WB

Platform ID

BAB592327484

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Ataxin 1 antibody [N76/8]
Cat. No.AB186265
HostMouse
IsotypeIgG2b
ReactivityHuman
ApplicationICC/IF, WB
ClonalityMonoclonal
Clone NumberN76/8
Concentration1 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Mouse Atxn1 aa 150-200. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein G
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.1% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine)
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ-mediated repression (By similarity). May be involved in RNA metabolism (By similarity). In concert with CIC and ATXN1L, involved in brain development (PubMed : 28288114). See full target information Atxn1

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