Anti-BACE1 antibody [027] - BSA and Azide free,Abcam,AB277127
Host
Rabbit
Reactivity
Human
Application
Flow Cyt (Intra), ICC
Platform ID
BAB408182123
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Product Specifications
Scientific Background
Specifications
NameAnti-BACE1 antibody [027] - BSA and Azide free
Cat. No.AB277127
HostRabbit
IsotypeIgG
ReactivityHuman
ApplicationFlow Cyt (Intra), ICC
ClonalityMonoclonal
Clone Number027
ImmunogenRecombinant Fragment Protein within Human BACE1 aa 1-500. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationConstituents: PBS
Storage+4°C
Regulatory StatusResearch Use Only
Scientific Background
Target data Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase (PubMed : 10656250, PubMed : 10677483, PubMed : 20354142). Cleaves CHL1 (By similarity). See full target information BACE1
Category Paths
Request a product
Please provide the required information below so that we can quickly source your products.