Anti-BACE1 antibody,Abcam,AB10716
Host
Rabbit
Reactivity
Mouse, Human
Application
WB, ICC/IF
Platform ID
BAB720688370
Abcam
Contact
Tel: +44 (0)1223 696000
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Product Specifications
Scientific Background
Specifications
NameAnti-BACE1 antibody
Cat. No.AB10716
HostRabbit
IsotypeIgG
ReactivityMouse, Human
ApplicationWB, ICC/IF
ClonalityPolyclonal
Concentration1 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Human BACE1 aa 450 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.05% Sodium azide Constituents: PBS, 0.1% BSA
Storage-20°C
Regulatory StatusResearch Use Only
Scientific Background
Target data Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase (PubMed : 10656250, PubMed : 10677483, PubMed : 20354142). Cleaves CHL1 (By similarity). See full target information BACE1
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
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