Anti-BATF3 antibody,Abcam,AB229727

Host

Rabbit

Reactivity

Human

Application

IP, WB

Platform ID

BAB659406535

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-BATF3 antibody
Cat. No.AB229727
HostRabbit
IsotypeIgG
ReactivityHuman
ApplicationIP, WB
ClonalityPolyclonal
Concentration0.785 mg/mL Batch dependent concentration
ImmunogenRecombinant Full Length Protein corresponding to Human BATF3.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7 Preservative: 0.025% Proclin 300 Constituents: PBS, 20% Glycerol (glycerin, glycerine)
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data AP-1 family transcription factor that controls the differentiation of CD8(+) thymic conventional dendritic cells in the immune system. Required for development of CD8-alpha(+) classical dendritic cells (cDCs) and related CD103(+) dendritic cells that cross-present antigens to CD8 T-cells and produce interleukin-12 (IL12) in response to pathogens (By similarity). Acts via the formation of a heterodimer with JUN family proteins that recognizes and binds DNA sequence 5'-TGA[CG]TCA-3' and regulates expression of target genes. See full target information BATF3

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