Anti-BLCAP antibody,Abcam,AB129775

Host

Rabbit

Reactivity

Mouse

Application

ICC/IF

Platform ID

BAB167552623

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-BLCAP antibody
Cat. No.AB129775
HostRabbit
IsotypeIgG
ReactivityMouse
ApplicationICC/IF
ClonalityPolyclonal
Concentration1 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Human BLCAP. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7 Preservative: 0.02% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine), 0.88% Sodium chloride
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Acts as a tumor suppressor; induces growth arrest at G(1)/S checkpoint and apoptosis via RB1-dependent and p53/TP53- and NF-kappa-B-independent mechanisms (PubMed : 16675915, PubMed : 17031575, PubMed : 21844121, PubMed : 26986503). Modulates expression of genes involved in the regulation of proliferation, cell cycle and apoptosis (PubMed : 17031575, PubMed : 21844121, PubMed : 26986503). See full target information BLCAP

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