Anti-BMPR1B antibody [MM0055-3E12],Abcam,AB78417

Host

Mouse

Reactivity

Human

Application

IHC-P, WB

Platform ID

BAB355696064

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-BMPR1B antibody [MM0055-3E12]
Cat. No.AB78417
HostMouse
IsotypeIgG2a
ReactivityHuman
ApplicationIHC-P, WB
ClonalityMonoclonal
Clone NumberMM0055-3E12
Concentration0.2 mg/mL Batch dependent concentration
ImmunogenRecombinant Full Length Protein corresponding to Human Bone morphogenetic protein receptor type-1B.
PurityAffinity purification Protein G
Appearance/FormLiquid
ShippingBlue Ice
FormulationConstituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP7/OP-1 and GDF5. Positively regulates chondrocyte differentiation through GDF5 interaction. See full target information Bone morphogenetic protein receptor type-1B

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