Anti-BNIP3 antibody [EPR4034],Abcam,AB109362
What is this antibody validated in? Anti-BNIP3 antibody [EPR4034] (ab109362) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Immunohistochemistry (IHC-P), Immunocytochemistry/immunofluorescence (ICC/IF) in Human, Mouse, Rat samples. What is the molecular weight of BNIP3? Anti-BNIP3 [EPR4034] (ab109362) specifically detects a band for BNIP3 (UniProt: Q12983) at a molecular weight of 22kDa. Trusted by the scientific community Anti-BNIP3 [EPR4034] (ab109362) was first used in a scientific publication in 2011 and has been cited over 70 times in peer-reviewed journals. Trial sizes available! Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 10µl. Discover our selection of trial-size antibodies. Specificity confirmed The specificity of Anti-BNIP3 antibody [EPR4034] (ab109362) has been confirmed by Western blot testing in BNIP3 Knockout HAP1 cells. Other related products We have a range of other formats of antibody clone [EPR4034] also available for your convenience: ab109362, Carrier free - ab219609 , Alexa Fluor® 488 - ab310999 , Alexa Fluor® 647 - ab311123 , Alexa Fluor® 594 - ab311755 , Alexa Fluor® 568 - ab313035 , Alexa Fluor® 555 - ab313236 , Alexa Fluor® 750 - ab320946 Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .
Host
Rabbit
Reactivity
Mouse, Rat, Human
Application
ICC/IF, IHC-P, WB
Platform ID
BAB793264781

Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data Apoptosis-inducing protein that can overcome BCL2 suppression. May play a role in repartitioning calcium between the two major intracellular calcium stores in association with BCL2. Involved in mitochondrial quality control via its interaction with SPATA18/MIEAP : in response to mitochondrial damage, participates in mitochondrial protein catabolic process (also named MALM) leading to the degradation of damaged proteins inside mitochondria. The physical interaction of SPATA18/MIEAP, BNIP3 and BNIP3L/NIX at the mitochondrial outer membrane regulates the opening of a pore in the mitochondrial double membrane in order to mediate the translocation of lysosomal proteins from the cytoplasm to the mitochondrial matrix. Plays an important role in the calprotectin (S100A8/A9)-induced cell death pathway. See full target information BNIP3
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
- Products>Primary Antibodies>Recombinant Antibodies
- Products>Trial Size Antibodies
Please provide the required information below so that we can quickly source your products.
