Anti-BRAF antibody [CL4004],Abcam,AB220032

Host

Mouse

Reactivity

Human

Application

WB, IHC-P

Platform ID

BAB043989433

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-BRAF antibody [CL4004]
Cat. No.AB220032
HostMouse
IsotypeIgG2b
ReactivityHuman
ApplicationWB, IHC-P
ClonalityMonoclonal
Clone NumberCL4004
Concentration1 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human BRAF aa 250-450. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine)
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Protein kinase involved in the transduction of mitogenic signals from the cell membrane to the nucleus (Probable). Phosphorylates MAP2K1, and thereby activates the MAP kinase signal transduction pathway (PubMed : 21441910, PubMed : 29433126). Phosphorylates PFKFB2 (PubMed : 36402789). May play a role in the postsynaptic responses of hippocampal neurons (PubMed : 1508179). See full target information BRAF

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