Anti-Bax antibody [E63],Abcam,AB32503

Anti-Bax antibody [E63] (ab32503) was developed by Abcam using patented rabbit monoclonal antibody technology and is validated for use in IHC-P, IP, WB, sELISA in human, mouse, rat samples. Anti-Bax antibody [E63] (ab32503) has been cited over 2479 times in peer reviewed journals and is trusted by the scientific community. Abcam's high quality manufacturing and validation processes ensure Anti-Bax antibody [E63] (ab32503) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility. The specificity of Anti-Bax antibody [E63] (ab32503) has been confirmed by testing in knockout samples. Anti-Bax antibody [E63] (ab32503) has 12 independent reviews from customers. Anti-Bax antibody [E63] (ab32503) specifically detects Bax (UniProt ID: Q07812; Molecular weight: 21kDa) and is sold in a convenient trial size to enable initial testing (20 µL) and larger sizes for subsequent scaling up experiments (100 µL and 1 mL). Conjugation-ready, carrier free format available for antibody clone E63 - ab216985 . Antibody clone E63 is also available pre-conjugated to a variety of labels for your convenience - HRP ( ab205822 ). The BAX gene (BCL2 Associated X) is a key player in the regulation of apoptosis, or programmed cell death, which is crucial for maintaining cellular homeostasis and preventing cancer. BAX is part of the BCL-2 protein family and promotes apoptosis by increasing mitochondrial membrane permeability, leading to the release of cytochrome c and activation of caspases. In oncology, BAX expression is regulated by the tumor suppressor protein p53, which is often mutated in cancer. Mutations or dysregulation of BAX can contribute to cancer development and progression by allowing cancer cells to survive. Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies . Shipping conditions update: ambient shipping This product will be delivered at ambient temperature instead of chilled – this is by design. Extensive stability testing confirmed that our products are suitable for shipment under ambient conditions and maintain expected quality. Why the change? It’s part of our commitment to more sustainable packaging solutions, with ambient deliveries using eco-friendly materials such as recyclable cardboard instead of polystyrene. What you need to know Ambient shipments come clearly marked on the delivery note. No ice will be included in ambient shipments, but mixed orders (ambient and cold-chain items) will still arrive with ice packs to protect temperature-sensitive products. Warranty coverage remains fully valid, aligned with our validated shipping method. Please store the product as per the datasheet instructions upon receipt. Find out more - https://www.abcam.com/en-us/support/shipping-storage-support/ambient-shipping