Anti-Bone Sialoprotein antibody [EPR23243-30],Abcam,AB270605

Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .

Host

Rabbit

Reactivity

Human, Mouse

Application

IHC-P, IHC-Fr

Platform ID

BAB793564637

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Bone Sialoprotein antibody [EPR23243-30]
Cat. No.AB270605
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse
ApplicationIHC-P, IHC-Fr
ClonalityMonoclonal
Clone NumberEPR23243-30
Concentration0.549 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Binds tightly to hydroxyapatite (PubMed : 11459848). Appears to form an integral part of the mineralized matrix (PubMed : 1818768). Probably important to cell-matrix interaction (PubMed : 1818768). Promotes adhesion and migration of various cells via the alpha-V/beta-3 integrin receptor (ITGAV : ITGB3) (PubMed : 10640428, PubMed : 11459848, PubMed : 24103036). See full target information IBSP

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