Anti-Borealin/CDCA8 antibody [OTI4G3],Abcam,AB279368

Host

Mouse

Reactivity

Human

Application

IHC-P

Platform ID

BAB981208318

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Borealin/CDCA8 antibody [OTI4G3]
Cat. No.AB279368
HostMouse
IsotypeIgG1
ReactivityHuman
ApplicationIHC-P
ClonalityMonoclonal
Clone NumberOTI4G3
Concentration1 mg/mL Batch dependent concentration
ImmunogenRecombinant Full Length Protein corresponding to Human CDCA8.
PurityAffinity purification Protein A/G
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.3 Preservative: 0.02% Sodium azide Constituents: 50% Glycerol (glycerin, glycerine), 1% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Major effector of the TTK kinase in the control of attachment-error-correction and chromosome alignment. See full target information CDCA8

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