Anti-C14orf133 antibody,Abcam,AB125084

Host

Rabbit

Reactivity

Human, Mouse

Application

IP, WB

Platform ID

BAB921925523

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-C14orf133 antibody
Cat. No.AB125084
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse
ApplicationIP, WB
ClonalityPolyclonal
ImmunogenSynthetic Peptide within Human VIPAS39 aa 400 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7 - 8 Preservative: 0.09% Sodium azide Constituents: 99% Tris citrate/phosphate
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Proposed to be involved in endosomal maturation implicating in part VPS33B. In epithelial cells, the VPS33B : VIPAS39 complex may play a role in the apical RAB11A-dependent recycling pathway and in the maintenance of the apical-basolateral polarity (PubMed : 20190753). May play a role in lysosomal trafficking, probably via association with the core HOPS complex in a discrete population of endosomes; the functions seems to be independent of VPS33B (PubMed : 19109425). May play a role in vesicular trafficking during spermatogenesis (By similarity). May be involved in direct or indirect transcriptional regulation of E-cadherin (By similarity). See full target information VIPAS39

Category Paths

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