Anti-C5a-R antibody [10/92],Abcam,AB117579

The production method has been switched from hybridoma to recombinant on 24th Oct 2025. What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .

Host

Rat

Reactivity

Mouse

Application

ICC/IF, Flow Cyt

Platform ID

BAB860943544

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-C5a-R antibody [10/92]
Cat. No.AB117579
HostRat
IsotypeIgG2a
ReactivityMouse
ApplicationICC/IF, Flow Cyt
ClonalityMonoclonal
Clone Number10/92
Concentration0.865 mg/mL Batch dependent concentration
ImmunogenCell preparation containing C5ar1 protein. The exact immunogen used to generate this antibody is proprietary information.
PurityIon exchange chromatography
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor : a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production. See full target information C5ar1

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