Anti-CCL21 antibody [MM0146-2H26],Abcam,AB89396

Reconstituted antibody should be aliquoted and can be stored frozen at < -20 for at least six months without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Host

Mouse

Reactivity

Human

Application

IHC-P, WB

Platform ID

BAB742977666

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-CCL21 antibody [MM0146-2H26]
Cat. No.AB89396
HostMouse
IsotypeIgG1
ReactivityHuman
ApplicationIHC-P, WB
ClonalityMonoclonal
Clone NumberMM0146-2H26
ImmunogenRecombinant Full Length Protein corresponding to Human CCL21.
PurityAffinity purification Protein G
Appearance/FormLyophilized
ShippingBlue Ice
FormulationConstituents: PBS
Storage-80°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Inhibits hemopoiesis and stimulates chemotaxis. Chemotactic in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Shows preferential activity towards naive T-cells. May play a role in mediating homing of lymphocytes to secondary lymphoid organs. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4. See full target information CCL21

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