Anti-CCM2 antibody [OTI2E4],Abcam,AB123930
Clone OTI2E4 (formerly 2E4).
Host
Mouse
Reactivity
Human, African green monkey
Application
ICC/IF, IHC-P, WB
Platform ID
BAB743377474
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Product Specifications
Scientific Background
Specifications
NameAnti-CCM2 antibody [OTI2E4]
Cat. No.AB123930
HostMouse
IsotypeIgG1
ReactivityHuman, African green monkey
ApplicationICC/IF, IHC-P, WB
ClonalityMonoclonal
Clone NumberOTI2E4
Concentration1 mg/mL Batch dependent concentration
ImmunogenRecombinant Full Length Protein corresponding to Human CCM2.
PurityAffinity purification
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.3 Preservative: 0.02% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine), 1% BSA
Storage-20°C
Regulatory StatusResearch Use Only
Scientific Background
Target data Component of the CCM signaling pathway which is a crucial regulator of heart and vessel formation and integrity. May act through the stabilization of endothelial cell junctions (By similarity). May function as a scaffold protein for MAP2K3-MAP3K3 signaling. Seems to play a major role in the modulation of MAP3K3-dependent p38 activation induced by hyperosmotic shock (By similarity). See full target information CCM2
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
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