Anti-CCR4 antibody [KH-4F5],Abcam,AB59550

Host

Mouse

Application

ICC/IF, Flow Cyt

Platform ID

BAB806158589

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-CCR4 antibody [KH-4F5]
Cat. No.AB59550
HostMouse
IsotypeIgG2a
ApplicationICC/IF, Flow Cyt
ClonalityMonoclonal
Clone NumberKH-4F5
Concentration1 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Human CCR4. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein G
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 Constituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data High affinity receptor for the C-C type chemokines CCL17/TARC, CCL22/MDC and CKLF isoform 1/CKLF1. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system. Can function as a chemoattractant homing receptor on circulating memory lymphocytes and as a coreceptor for some primary HIV-2 isolates. In the CNS, could mediate hippocampal-neuron survival. See full target information CCR4

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