Anti-CCR5 antibody [12D1] - BSA and Azide free,Abcam,AB212302

Host

Mouse

Reactivity

Human

Application

IHC-Fr

Platform ID

BAB431171083

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-CCR5 antibody [12D1] - BSA and Azide free
Cat. No.AB212302
HostMouse
IsotypeIgG2a
ReactivityHuman
ApplicationIHC-Fr
ClonalityMonoclonal
Clone Number12D1
ImmunogenNative Full Length Protein corresponding to Human CCR5.
PurityAffinity purification Protein A/G
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Constituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Receptor for a number of inflammatory CC-chemokines including CCL3/MIP-1-alpha, CCL4/MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation. Participates in T-lymphocyte migration to the infection site by acting as a chemotactic receptor (PubMed : 30713770).. (Microbial infection) Acts as a coreceptor (CD4 being the primary receptor) of human immunodeficiency virus-1/HIV-1. See full target information CCR5

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