Anti-CD146 antibody,Abcam,AB203118

Host

Rabbit

Reactivity

Rat, Human

Application

IHC-P

Platform ID

BAB433270075

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-CD146 antibody
Cat. No.AB203118
HostRabbit
IsotypeIgG
ReactivityRat, Human
ApplicationIHC-P
ClonalityPolyclonal
Concentration0.1 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Human MCAM aa 200-250 conjugated to Keyhole Limpet Haemocyanin. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.02% Proclin 300 Constituents: 50% Glycerol (glycerin, glycerine), 48.98% TBS, 1X, 1% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as a surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration. See full target information MCAM

Category Paths

Request a product

Please provide the required information below so that we can quickly source your products.