Anti-CD146 antibody [EPR3208],Abcam,AB75769

Anti-CD146 antibody [EPR3208] (ab75769) was developed by Abcam using patented rabbit monoclonal antibody technology and is validated for use in Flow Cyt (Intra), ICC/IF, IHC-P, WB in human, mouse, rat samples. Anti-CD146 antibody [EPR3208] (ab75769) has been cited over 149 times in peer reviewed journals and is trusted by the scientific community. Abcam's high quality manufacturing and validation processes ensure Anti-CD146 antibody [EPR3208] (ab75769) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility. The specificity of Anti-CD146 antibody [EPR3208] (ab75769) has been confirmed by testing in knockout samples. Anti-CD146 antibody [EPR3208] (ab75769) has 40 independent reviews from customers. Anti-CD146 antibody [EPR3208] (ab75769) specifically detects CD146 (UniProt ID: P43121; Molecular weight: 69kDa) and is sold in 100 µL and 1 mL selling sizes. Conjugation-ready, carrier free format available for antibody clone EPR3208 - ab210072 . Antibody clone EPR3208 is also available pre-conjugated to a variety of labels for your convenience - Alexa Fluor® 488, PE, PerCP, Biotin, APC, HRP, Alexa Fluor® 647, Alexa Fluor® 555 ( ab196448 , ab209298 , ab216361 , ab217072 , ab303023 , ab303024 , ab305213 , ab307390 ). Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .

Host

Rabbit

Reactivity

Mouse, Rat, Human

Application

ICC/IF, IHC-P, WB, Flow Cyt (Intra)

Platform ID

BAB995801310

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-CD146 antibody [EPR3208]
Cat. No.AB75769
HostRabbit
IsotypeIgG
ReactivityMouse, Rat, Human
ApplicationICC/IF, IHC-P, WB, Flow Cyt (Intra)
ClonalityMonoclonal
Clone NumberEPR3208
Concentration0.118 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as a surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration. See full target information MCAM

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