Anti-CD20 antibody [10F381(rituximab)] - Rabbit IgG (Chimeric),Abcam,AB275973

This rabbit monoclonal chimeric antibody was made using the variable domain sequences of the original human IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Host

Rabbit

Reactivity

Human, Cynomolgus monkey, Rhesus monkey

Application

Flow Cyt

Platform ID

BAB747575458

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-CD20 antibody [10F381(rituximab)] - Rabbit IgG (Chimeric)
Cat. No.AB275973
HostRabbit
IsotypeIgG
ReactivityHuman, Cynomolgus monkey, Rhesus monkey
ApplicationFlow Cyt
ClonalityMonoclonal
Clone Number10F381(rituximab)
Concentration1 mg/mL Batch dependent concentration
ImmunogenCell preparation containing MS4A1 protein. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.02% Proclin 300 Constituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data B-lymphocyte-specific membrane protein that plays a role in the regulation of cellular calcium influx necessary for the development, differentiation, and activation of B-lymphocytes (PubMed : 12920111, PubMed : 3925015, PubMed : 7684739). Functions as a store-operated calcium (SOC) channel component promoting calcium influx after activation by the B-cell receptor/BCR (PubMed : 12920111, PubMed : 18474602, PubMed : 7684739). See full target information MS4A1

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