Anti-CD20 antibody [EP459Y] - Mouse IgG2a (Chimeric),Abcam,AB279299

This mouse monoclonal chimeric antibody has been engineered from a RabMAb parent antibody ( ab78237 ). By necessity, some rabbit sequence is retained as part of the variable domain. When multiplexing with other rabbit-derived antibodies, using cross absorbed Fc-reactive secondary antibodies are recommended.

Host

Mouse

Reactivity

Human

Application

IP, ICC, Flow Cyt (Intra), WB

Platform ID

BAB872637928

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-CD20 antibody [EP459Y] - Mouse IgG2a (Chimeric)
Cat. No.AB279299
HostMouse
IsotypeIgG2a
ReactivityHuman
ApplicationIP, ICC, Flow Cyt (Intra), WB
ClonalityMonoclonal
Clone NumberEP459Y
Concentration0.813 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data B-lymphocyte-specific membrane protein that plays a role in the regulation of cellular calcium influx necessary for the development, differentiation, and activation of B-lymphocytes (PubMed : 12920111, PubMed : 3925015, PubMed : 7684739). Functions as a store-operated calcium (SOC) channel component promoting calcium influx after activation by the B-cell receptor/BCR (PubMed : 12920111, PubMed : 18474602, PubMed : 7684739). See full target information MS4A1

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