Anti-CD276 antibody [SP206],Abcam,AB227670

What is this antibody validated in? Anti-CD276 antibody [SP206] (ab227670) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Immunohistochemistry (IHC-P) in Human samples. What is the molecular weight of CD276? Anti-CD276 [SP206] (ab227670) specifically detects a band for CD276 (UniProt: Q5ZPR3) at a molecular weight of 57kDa. Collaboration Anti-CD276 [SP206] (ab227670) is a clone from the portfolio of Spring Bioscience (Roche) SP clones which have been optimised for immunohistochemistry (IHC). Trial sizes available! Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 10µl. Discover our selection of trial-size antibodies. Specificity confirmed The specificity of Anti-CD276 antibody [SP206] (ab227670) has been confirmed by Western blot testing in CD276 Knockout HeLa cell line, ab266658 . Other related products We have a range of other formats of antibody clone [SP206] also available for your convenience: ab227670, Carrier free - ab240407 , Carrier free - ab246794 , Alexa Fluor® 488 - ab320516 , Alexa Fluor® 647 - ab320517 , Alexa Fluor® 555 - ab320518 , Alexa Fluor® 594 - ab320519 , PE - ab320520 , APC - ab320521 , Alexa Fluor® 750 - ab321445 Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .

Host

Rabbit

Reactivity

Human

Application

WB, IHC-P

Platform ID

BAB624112220

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-CD276 antibody [SP206]
Cat. No.AB227670
HostRabbit
IsotypeIgG
ReactivityHuman
ApplicationWB, IHC-P
ClonalityMonoclonal
Clone NumberSP206
Concentration0.23 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.1% Sodium azide Constituents: PBS, 1% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data May participate in the regulation of T-cell-mediated immune response. May play a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. May be involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. Could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy. Both isoform 1 and isoform 2 appear to be redundant in their ability to modulate CD4 T-cell responses. Isoform 2 is shown to enhance the induction of cytotoxic T-cells and selectively stimulates interferon gamma production in the presence of T-cell receptor signaling. See full target information CD276

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