Anti-CD41 antibody [EPR4330],Abcam,AB134131

What is this antibody validated in? Anti-CD41 antibody [EPR4330] (ab134131) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Immunohistochemistry (IHC-P), Immunocytochemistry/immunofluorescence (ICC/IF) in Human, Mouse samples. What is the molecular weight of CD41? Anti-CD41 [EPR4330] (ab134131) specifically detects a band for CD41 (UniProt: P08514) at a molecular weight of 113kDa. Trusted by the scientific community Anti-CD41 [EPR4330] (ab134131) was first used in a scientific publication in 2012 and has been cited over 20 times in peer-reviewed journals. Trial sizes available! Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 10µl. Discover our selection of trial-size antibodies. Other related products We have a range of other formats of antibody clone [EPR4330] also available for your convenience: ab134131, HRP - ab194981 , Carrier free - ab229448 , Carrier free - ab271906 , Alexa Fluor® 647 - ab308537 , Alexa Fluor® 488 - ab311002 , Alexa Fluor® 568 - ab313040 , Alexa Fluor® 555 - ab313241 , Alexa Fluor® 750 - ab321077 Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies . Species reactivity Rat: We have preliminary internal testing data to indicate this antibody may not react with this species. Please contact us for more information.

Host

Rabbit

Reactivity

Mouse, Human

Application

WB, ICC/IF, IHC-P

Platform ID

BAB501848406

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-CD41 antibody [EPR4330]
Cat. No.AB134131
HostRabbit
IsotypeIgG
ReactivityMouse, Human
ApplicationWB, ICC/IF, IHC-P
ClonalityMonoclonal
Clone NumberEPR4330
Concentration0.661 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: 59% Tris glycine, 40% Glycerol (glycerin, glycerine), 0.88% Sodium chloride, 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain (By similarity). Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen (PubMed : 9111081). This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface (By similarity). See full target information ITGA2B

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