Anti-CD41 antibody [MEM-06],Abcam,AB2211

Host

Mouse

Reactivity

Human

Application

Flow Cyt

Platform ID

BAB376885888

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-CD41 antibody [MEM-06]
Cat. No.AB2211
HostMouse
IsotypeIgG1
ReactivityHuman
ApplicationFlow Cyt
ClonalityMonoclonal
Clone NumberMEM-06
Concentration1 mg/mL Batch dependent concentration
ImmunogenCell preparation containing ITGA2B protein. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.097% Sodium azide Constituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain (By similarity). Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen (PubMed : 9111081). This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface (By similarity). See full target information ITGA2B

Category Paths

Request a product

Please provide the required information below so that we can quickly source your products.