Anti-CD41 antibody [MWReg30],Abcam,AB33661
The azide free version is ab94960 . Clone MWReg30 has been reported to inhibit PMA induced aggregation in vitro and to induce hypothermia in vivo.
Host
Rat
Reactivity
Mouse
Application
Flow Cyt
Platform ID
BAB689392135
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface. See full target information Itga2b
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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