Anti-CD41 antibody [MWReg30] - Low endotoxin, Azide free,Abcam,AB206636

Endotoxin level is less than 0.01 EU/μg of the protein, as determined by the LAL test.

Host

Rat

Reactivity

Mouse

Application

Flow Cyt

Platform ID

BAB001898382

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-CD41 antibody [MWReg30] - Low endotoxin, Azide free
Cat. No.AB206636
HostRat
IsotypeIgG1
ReactivityMouse
ApplicationFlow Cyt
ClonalityMonoclonal
Clone NumberMWReg30
Concentration1 mg/mL Batch dependent concentration
ImmunogenCell preparation containing Itga2b protein. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein G
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Constituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface. See full target information Itga2b

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