Anti-CD45 antibody [IBL-3/16],Abcam,AB23910
What is this antibody validated in? Anti-CD45 antibody [IBL-3/16] (ab23910) is a rat monoclonal antibody and is validated for use in Flow Cytometry (Flow Cyt), Immunoprecipitation (IP), Immunohistochemistry (IHC-Fr), Immunocytochemistry/immunofluorescence (ICC/IF) in Mouse samples. Trusted by the scientific community Anti-CD45 [IBL-3/16] (ab23910) was first used in a scientific publication in 2005 and has been cited over 20 times in peer-reviewed journals.
Host
Rat
Reactivity
Mouse
Application
ICC/IF, Flow Cyt, IHC-Fr, IP
Platform ID
BAB565029329
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Product Specifications
Scientific Background
Specifications
NameAnti-CD45 antibody [IBL-3/16]
Cat. No.AB23910
HostRat
IsotypeIgG1
ReactivityMouse
ApplicationICC/IF, Flow Cyt, IHC-Fr, IP
ClonalityMonoclonal
Clone NumberIBL-3/16
Concentration0.5 mg/mL Batch dependent concentration
ImmunogenCell preparation containing Ptprc protein. The exact immunogen used to generate this antibody is proprietary information.
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 Preservative: 0.09% Sodium azide Constituents: PBS, 0.1% BSA
Storage-20°C
Regulatory StatusResearch Use Only
Scientific Background
Target data Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN (By similarity). Dephosphorylates LYN, and thereby modulates LYN activity. See full target information Ptprc
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
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