Anti-CD45RO antibody [UCHL1],Abcam,AB23
What is this antibody validated in? Anti-CD45RO antibody [UCH-L1] (ab23) is a mouse monoclonal antibody and is validated for use in Western Blot (WB), Flow Cytometry (Flow Cyt), Immunohistochemistry (IHC-P) in Human samples. What is the molecular weight of CD45RO? Anti-CD45RO [UCH-L1] (ab23) specifically detects a band for CD45RO (UniProt: P08575) at a molecular weight of 131kDa. Trusted by the scientific community Anti-CD45RO [UCH-L1] (ab23) was first used in a scientific publication in 2002 and has been cited over 20 times in peer-reviewed journals.
Host
Mouse
Reactivity
Human
Application
IHC-P, Flow Cyt, WB
Platform ID
BAB815254221
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor (PubMed : 35767951). Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity (By similarity).. (Microbial infection) Acts as a receptor for human cytomegalovirus protein UL11 and mediates binding of UL11 to T-cells, leading to reduced induction of tyrosine phosphorylation of multiple signaling proteins upon T-cell receptor stimulation and impaired T-cell proliferation. See full target information PTPRC
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
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