Anti-CD59 antibody [p282 (H19)],Abcam,AB79520

Host

Mouse

Reactivity

Human, Baboon

Application

IHC-P, Flow Cyt

Platform ID

BAB253622554

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-CD59 antibody [p282 (H19)]
Cat. No.AB79520
HostMouse
IsotypeIgG2a
ReactivityHuman, Baboon
ApplicationIHC-P, Flow Cyt
ClonalityMonoclonal
Clone Numberp282 (H19)
ImmunogenFull Length Protein corresponding to Human CD59. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 Preservative: 0.09% Sodium azide Constituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase.. The soluble form from urine retains its specific complement binding activity, but exhibits greatly reduced ability to inhibit MAC assembly on cell membranes. See full target information CD59

Category Paths

Request a product

Please provide the required information below so that we can quickly source your products.