Anti-CD68 antibody,Abcam,AB125212

Anti-CD68 antibody (ab125212) is a rabbit polyclonal antibody and is validated for use in IHC-Fr, IHC-P and WB. Anti-CD68 antibody (ab125212) was first used in a scientific publication in 2012 and has been cited over 726 times in peer reviewed journals. It's performance in Western blot, immunofluorescence and IHC in human, mouse and rat samples is trusted by the scientific community. Abcam's high quality validation processes ensure Anti-CD68 antibody (ab125212) has high sensitivity and specificity. Anti-CD68 antibody (ab125212) has 55 independent reviews from customers. Anti-CD68 antibody (ab125212) specifically detects CD68 (UniProt ID: P31996; Molecular weight: 33kDa) and is sold in 100 ug selling sizes. CD68 levels is implicated in autoimmune conditions like rheumatoid arthritis, where macrophages contribute to joint inflammation and damage. Cited in over 924 publications.

Host

Rabbit

Reactivity

Mouse, Rat

Application

IHC-P, WB

Platform ID

BAB129459652

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-CD68 antibody
Cat. No.AB125212
HostRabbit
IsotypeIgG
ReactivityMouse, Rat
ApplicationIHC-P, WB
ClonalityPolyclonal
Concentration0.5 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Mouse Cd68 aa 300 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationConstituents: 5.61% Trehalose, 0.45% Sodium chloride, 0.1% Disodium hydrogenorthophosphate
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells. See full target information Cd68

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