Anti-CD68 antibody [EPR20545],Abcam,AB213363

Product Specifications Anti-CD68 antibody [EPR20545] (ab213363) was developed by Abcam using patented rabbit monoclonal antibody technology and is validated for use in ICC/IF, IHC-P, WB, mIHC in human samples. Anti-CD68 antibody [EPR20545] (ab213363) specifically detects CD68 (UniProt ID: P34810; Molecular weight: 35kDa) and is sold in a convenient trial size to enable initial testing (20 µL) and larger sizes for subsequent scaling up experiments (100 µL and 1 mL). Quality and Validation Abcam's high quality manufacturing and validation processes ensure Anti-CD68 antibody [EPR20545] (ab213363) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility. Anti-CD68 antibody [EPR20545] (ab213363) has been cited over 118 times in peer reviewed journals and is trusted by the scientific community. Anti-CD68 antibody [EPR20545] (ab213363) has 5 independent reviews from customers. Related Products Conjugation-ready, carrier free format available for antibody clone EPR20545 - ab227458 . Antibody clone EPR20545 is also available pre-conjugated to a variety of labels for your convenience - Alexa Fluor® 647, Alexa Fluor® 488, Alexa Fluor® 594, Alexa Fluor® 555 ( ab224029 , ab277276 , ab277938 , ab280860 ). Target Information CD68 is a transmembrane glycoprotein primarily found on macrophages, essential for phagocytosis and antigen presentation. It plays a role in various pathological conditions, such as neuroinflammatory diseases, by clearing cellular debris and modulating immune responses. CD68 expression is linked to several diseases involving macrophage activity, including cancer, neuroinflammation, granular cell tumor, and histiocytic sarcoma. Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .

Host

Rabbit

Reactivity

Human

Application

mIHC, IHC-P, ICC/IF, WB

Platform ID

BAB691990887

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-CD68 antibody [EPR20545]
Cat. No.AB213363
HostRabbit
IsotypeIgG
ReactivityHuman
ApplicationmIHC, IHC-P, ICC/IF, WB
ClonalityMonoclonal
Clone NumberEPR20545
Concentration0.657 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells. See full target information CD68

Category Paths

Request a product

Please provide the required information below so that we can quickly source your products.