Anti-CD70 antibody [FR70] - Low endotoxin, Azide free,Abcam,AB171218

Endotoxin Level: Less than 0.001 ng/ug antibody, as determined by the LAL assay.

Host

Rat

Reactivity

Mouse

Application

Flow Cyt

Platform ID

BAB692390695

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-CD70 antibody [FR70] - Low endotoxin, Azide free
Cat. No.AB171218
HostRat
IsotypeIgG2b
ReactivityMouse
ApplicationFlow Cyt
ClonalityMonoclonal
Clone NumberFR70
Concentration1 mg/mL Batch dependent concentration
PurityAffinity purification
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 Constituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Expressed at the plasma membrane of B cells, it is the ligand of the CD27 receptor which is specifically expressed at the surface of T cells (PubMed : 28011863, PubMed : 28011864, PubMed : 8387892). The CD70-CD27 signaling pathway mediates antigen-specific T cell activation and expansion which in turn provides immune surveillance of B cells (PubMed : 28011863, PubMed : 28011864). See full target information CD70

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