Anti-CD86 antibody [EP1158-37],Abcam,AB269587
What is this antibody validated in? Anti-CD86 antibody [EP1158-37] (ab269587) is a rabbit monoclonal antibody and is validated for use in Western Blot (WB), Immunohistochemistry (IHC-P) in Human samples. What is the molecular weight of CD86? Anti-CD86 [EP1158-37] (ab269587) specifically detects a band for CD86 (UniProt: P42081) at a molecular weight of 38kDa. Trial sizes available! Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 10µl. Discover our selection of trial-size antibodies. Specificity confirmed The specificity of Anti-CD86 antibody [EP1158-37] (ab269587) has been confirmed by Western blot testing in CD86 Knockout Raji cells. Other related products We have a range of other formats of antibody clone [EP1158-37] also available for your convenience: ab269587, Carrier free - ab269593 Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents .
Host
Rabbit
Reactivity
Human
Application
IHC-P, WB
Platform ID
BAB318802517
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4 (PubMed : 12196291). May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation (PubMed : 7527824). Also involved in the regulation of B cells function, plays a role in regulating the level of IgG(1) produced. Upon CD40 engagement, activates NF-kappa-B signaling pathway via phospholipase C and protein kinase C activation (By similarity).. Isoform 2. Interferes with the formation of CD86 clusters, and thus acts as a negative regulator of T-cell activation.. (Microbial infection) Acts as a receptor for adenovirus subgroup B. See full target information CD86
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
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