Anti-CD86 antibody [EPR21962],Abcam,AB239075
What is this antibody validated in? Anti-CD86 antibody [EPR21962] (ab239075) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Flow Cytometry (Flow Cyt), Immunoprecipitation (IP), Immunocytochemistry/immunofluorescence (ICC/IF) in Human samples. What is the molecular weight of CD86? Anti-CD86 [EPR21962] (ab239075) specifically detects a band for CD86 (UniProt: P42081) at a molecular weight of 38kDa. Trusted by the scientific community Anti-CD86 [EPR21962] (ab239075) was first used in a scientific publication in 2018 and has been cited over 20 times in peer-reviewed journals. Trial sizes available! Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 10µl. Discover our selection of trial-size antibodies. Specificity confirmed The specificity of Anti-CD86 antibody [EPR21962] (ab239075) has been confirmed by Western blot testing in CD86 Knockout Raji cells. Other related products We have a range of other formats of antibody clone [EPR21962] also available for your convenience: ab239075, Carrier free - ab242020 , Alexa Fluor® 647 - ab288358 , Alexa Fluor® 488 - ab290990 , Alexa Fluor® 594 - ab303578 Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .
Host
Rabbit
Reactivity
Human
Application
WB, ICC/IF, Flow Cyt, IP
Platform ID
BAB568827505
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4 (PubMed : 12196291). May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation (PubMed : 7527824). Also involved in the regulation of B cells function, plays a role in regulating the level of IgG(1) produced. Upon CD40 engagement, activates NF-kappa-B signaling pathway via phospholipase C and protein kinase C activation (By similarity).. Isoform 2. Interferes with the formation of CD86 clusters, and thus acts as a negative regulator of T-cell activation.. (Microbial infection) Acts as a receptor for adenovirus subgroup B. See full target information CD86
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
- Products>Primary Antibodies>Recombinant Antibodies
- Products>Trial Size Antibodies
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