Anti-CD9 antibody [EPR23105-121],Abcam,AB236630
Product Specifications Anti-CD9 antibody [EPR23105-121] (ab236630) was developed by Abcam using patented rabbit monoclonal antibody technology and is validated for use in Flow Cyt, ICC/IF, IHC-P, IP, WB in human samples. Anti-CD9 antibody [EPR23105-121] (ab236630) specifically detects CD9 (UniProt ID: P21926; Molecular weight: 25kDa) and is sold in 100 µL and 1 mL selling sizes. Quality and Validation Abcam's high quality manufacturing and validation processes ensure Anti-CD9 antibody [EPR23105-121] (ab236630) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility. The specificity of Anti-CD9 antibody [EPR23105-121] (ab236630) has been confirmed by testing in knockout samples. Anti-CD9 antibody [EPR23105-121] (ab236630) has been cited over 65 times in peer reviewed journals and is trusted by the scientific community. Related Products Conjugation-ready, carrier free format available for antibody clone EPR23105-121 - ab263023 . Antibody clone EPR23105-121 is also available pre-conjugated to a variety of labels for your convenience - Alexa Fluor® 488, Alexa Fluor® 647 ( ab267502 , ab267503 ). Target Information CD9 also known as p24 is a member of the tetraspanin family, which includes proteins involved in various cellular processes. CD9 (p24) plays a significant role in cancer progression and metastasis by influencing cell adhesion, migration, and signaling. CD9 (p24) is found on the surface of cancer cells and within exosomes, impacting cancer progression and therapy resistance. CD9's role in cancer is complex, as it can both suppress and promote tumor growth depending on the context. The protein's interactions within tetraspanin-enriched microdomains (TEMs) are crucial for its function. Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .
Host
Rabbit
Reactivity
Human
Application
IHC-P, WB, Flow Cyt, IP, ICC/IF
Platform ID
BAB818952445
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data Integral membrane protein associated with integrins, which regulates different processes, such as sperm-egg fusion, platelet activation and aggregation, and cell adhesion (PubMed : 14575715, PubMed : 18541721, PubMed : 8478605). Present at the cell surface of oocytes and plays a key role in sperm-egg fusion, possibly by organizing multiprotein complexes and the morphology of the membrane required for the fusion (By similarity). In myoblasts, associates with CD81 and PTGFRN and inhibits myotube fusion during muscle regeneration (By similarity). In macrophages, associates with CD81 and beta-1 and beta-2 integrins, and prevents macrophage fusion into multinucleated giant cells specialized in ingesting complement-opsonized large particles (PubMed : 12796480). Also prevents the fusion between mononuclear cell progenitors into osteoclasts in charge of bone resorption (By similarity). Acts as a receptor for PSG17 (By similarity). Involved in platelet activation and aggregation (PubMed : 18541721). Regulates paranodal junction formation (By similarity). Involved in cell adhesion, cell motility and tumor metastasis (PubMed : 7511626, PubMed : 8478605). See full target information CD9
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
- Products>Primary Antibodies>Recombinant Antibodies
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