Anti-CD9 antibody [TS9] - BSA and Azide free,Abcam,AB58989

What is this antibody validated in? Anti-CD9 antibody [TS9] - BSA and Azide free (ab58989) is a mouse monoclonal antibody and is validated for use in Western Blot (WB) in Human samples. What is the molecular weight of CD9? Anti-CD9 [TS9] - BSA and Azide free (ab58989) specifically detects a band for CD9 (UniProt: P21926) at a molecular weight of 24kDa. Trusted by the scientific community Anti-CD9 [TS9] - BSA and Azide free (ab58989) was first used in a scientific publication in 2007 and has been cited over 10 times in peer-reviewed journals. Specificity confirmed The specificity of Anti-CD9 antibody [TS9] - BSA and Azide free (ab58989) has been confirmed by Western blot testing in CD9 Knockout HeLa cell line, ab255375 .

Host

Mouse

Reactivity

Human

Application

WB

Platform ID

BAB569027409

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-CD9 antibody [TS9] - BSA and Azide free
Cat. No.AB58989
HostMouse
IsotypeIgG1
ReactivityHuman
ApplicationWB
ClonalityMonoclonal
Clone NumberTS9
ImmunogenCell preparation containing CD9 protein. The exact immunogen used to generate this antibody is proprietary information.
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.3 - 7.5 Constituents: PBS
Storage+4°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Integral membrane protein associated with integrins, which regulates different processes, such as sperm-egg fusion, platelet activation and aggregation, and cell adhesion (PubMed : 14575715, PubMed : 18541721, PubMed : 8478605). Present at the cell surface of oocytes and plays a key role in sperm-egg fusion, possibly by organizing multiprotein complexes and the morphology of the membrane required for the fusion (By similarity). In myoblasts, associates with CD81 and PTGFRN and inhibits myotube fusion during muscle regeneration (By similarity). In macrophages, associates with CD81 and beta-1 and beta-2 integrins, and prevents macrophage fusion into multinucleated giant cells specialized in ingesting complement-opsonized large particles (PubMed : 12796480). Also prevents the fusion between mononuclear cell progenitors into osteoclasts in charge of bone resorption (By similarity). Acts as a receptor for PSG17 (By similarity). Involved in platelet activation and aggregation (PubMed : 18541721). Regulates paranodal junction formation (By similarity). Involved in cell adhesion, cell motility and tumor metastasis (PubMed : 7511626, PubMed : 8478605). See full target information CD9

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