Anti-CDKN2A/p16INK4a antibody,Abcam,AB264192

Host

Rabbit

Reactivity

Human

Application

IHC-P, WB, IP

Platform ID

BAB071076425

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-CDKN2A/p16INK4a antibody
Cat. No.AB264192
HostRabbit
IsotypeIgG
ReactivityHuman
ApplicationIHC-P, WB, IP
ClonalityPolyclonal
Concentration0.2 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Human CDKN2A aa 100 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 6.8 - 7.4 Preservative: 0.09% Sodium azide Constituents: Tris buffered saline, 0.1% BSA
Storage+4°C
Regulatory StatusResearch Use Only

Scientific Background

Target data The protein expressed by the gene CDKN2A acts as a negative regulator of normal cell proliferation by strongly interacting with CDK4 and CDK6. This interaction inhibits the ability of CDK4 and CDK6 to interact with cyclins D and to phosphorylate the retinoblastoma protein. This supplementary information is collated from multiple sources and compiled automatically. See full target information CDKN2A

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