Anti-CDKN2A/p16INK4a antibody - N-terminal,Abcam,AB189034

Product Specifications Anti-CDKN2A/p16INK4a antibody - N-terminal (ab189034) is a rabbit polyclonal antibody and is validated for use in ICC/IF, IHC-P, WB in human, mouse samples. Anti-CDKN2A/p16INK4a antibody - N-terminal (ab189034) specifically detects CDKN2A/p16INK4a (UniProt ID: P42771; Molecular weight: 17kDa) and is sold in 50 µL selling sizes. Quality and Validation Abcam's high quality validation processes ensure Anti-CDKN2A/p16INK4a antibody - N-terminal (ab189034) has high sensitivity and specificity. Anti-CDKN2A/p16INK4a antibody - N-terminal (ab189034) has been cited over 72 times in peer reviewed journals and is trusted by the scientific community. Anti-CDKN2A/p16INK4a antibody - N-terminal (ab189034) has 4 independent reviews from customers. Target Information CDKN2A, also known as cyclin-dependent kinase inhibitor 2A, is a crucial tumor suppressor gene located on chromosome 9p211. It encodes two proteins, p16INK4a and p14ARF, both of which play significant roles in regulating the cell cycle. p16INK4a inhibits cyclin-dependent kinases 4 and 6 (CDK4 and CDK6), preventing the progression from the G1 to S phase of the cell cycle. This inhibition is vital for controlling cell proliferation and preventing tumor growth. Mutations or deletions in CDKN2A are frequently associated with various cancers, including melanoma, pancreatic cancer, and head and neck squamous cell carcinoma.