Anti-CEACAM5 + CEACAM6 antibody [NCRC16 (AKA 161)],Abcam,AB22705

Host

Mouse

Reactivity

Human

Application

ICC/IF, IHC-P

Platform ID

BAB634207372

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-CEACAM5 + CEACAM6 antibody [NCRC16 (AKA 161)]
Cat. No.AB22705
HostMouse
IsotypeIgG1
ReactivityHuman
ApplicationICC/IF, IHC-P
ClonalityMonoclonal
Clone NumberNCRC16 (AKA 161)
Concentration1 mg/mL Batch dependent concentration
PurityAffinity purification Protein A/G
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.02% Sodium azide Constituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Cell surface glycoprotein that plays a role in cell adhesion, intracellular signaling and tumor progression (PubMed : 10864933, PubMed : 10910050, PubMed : 2803308). Mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6 (PubMed : 2803308). Plays a role as an oncogene by promoting tumor progression; induces resistance to anoikis of colorectal carcinoma cells (PubMed : 10910050).. (Microbial infection) Receptor for E.coli Dr adhesins. Binding of E.coli Dr adhesins leads to dissociation of the homodimer. See full target information CEACAM5 Additional targets CEACAM6

Category Paths

Request a product

Please provide the required information below so that we can quickly source your products.