Anti-CEACAM5 antibody [26/3/13] - BSA and Azide free,Abcam,AB4451

What is this antibody validated in? Anti-CEACAM5 antibody [26/3/13] - BSA and Azide free (ab4451) is a mouse recombinant monoclonal antibody and is validated for use in Immunohistochemistry (IHC-P), ELISA in Human samples. Trusted by the scientific community Anti-CEACAM5 [26/3/13] - BSA and Azide free (ab4451) was first used in a scientific publication in 2003 and has been cited over 10 times in peer-reviewed journals. What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .

Host

Mouse

Reactivity

Human

Application

I-ELISA, IHC-P

Platform ID

BAB821651149

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-CEACAM5 antibody [26/3/13] - BSA and Azide free
Cat. No.AB4451
HostMouse
IsotypeIgG1
ReactivityHuman
ApplicationI-ELISA, IHC-P
ClonalityMonoclonal
Clone Number26/3/13
Concentration1.035 mg/mL Batch dependent concentration
ImmunogenNative Full Length Protein corresponding to Human CEACAM5.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Constituents: PBS
Storage+4°C|-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Cell surface glycoprotein that plays a role in cell adhesion, intracellular signaling and tumor progression (PubMed : 10864933, PubMed : 10910050, PubMed : 2803308). Mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6 (PubMed : 2803308). Plays a role as an oncogene by promoting tumor progression; induces resistance to anoikis of colorectal carcinoma cells (PubMed : 10910050).. (Microbial infection) Receptor for E.coli Dr adhesins. Binding of E.coli Dr adhesins leads to dissociation of the homodimer. See full target information CEACAM5

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