Anti-CEACAM5 antibody [BLR198J] - BSA free,Abcam,AB314055

What is this antibody validated in? Anti-CEACAM5 antibody [BLR198J] - BSA free (ab314055) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC-P) in Human samples. What is the molecular weight of CEACAM5? Anti-CEACAM5 [BLR198J] - BSA free (ab314055) specifically detects a band for CEACAM5 (UniProt: P06731) at a molecular weight of 76kDa. REACH authorisation Abcam has not and does not intend to apply for the REACH Authorisation of customers' uses of products that contain European Authorisation list (Annex XIV) substances. It is the responsibility of our customers to check the necessity of application of REACH Authorisation, and any other relevant authorisations, for their intended uses.

Host

Rabbit

Reactivity

Human

Application

IP, ICC, IHC-P, WB

Platform ID

BAB134157396

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-CEACAM5 antibody [BLR198J] - BSA free
Cat. No.AB314055
HostRabbit
IsotypeIgG
ReactivityHuman
ApplicationIP, ICC, IHC-P, WB
ClonalityMonoclonal
Clone NumberBLR198J
Concentration1 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human CEACAM5 aa 1-700. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.8 - 8.6 Preservative: 0.09% Sodium azide Constituents: 98% Borate buffered saline
Storage+4°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Cell surface glycoprotein that plays a role in cell adhesion, intracellular signaling and tumor progression (PubMed : 10864933, PubMed : 10910050, PubMed : 2803308). Mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6 (PubMed : 2803308). Plays a role as an oncogene by promoting tumor progression; induces resistance to anoikis of colorectal carcinoma cells (PubMed : 10910050).. (Microbial infection) Receptor for E.coli Dr adhesins. Binding of E.coli Dr adhesins leads to dissociation of the homodimer. See full target information CEACAM5

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