Anti-CEACAM5 antibody [CEA31],Abcam,AB193372

Host

Mouse

Reactivity

Human

Application

IHC-P

Platform ID

BAB614416876

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-CEACAM5 antibody [CEA31]
Cat. No.AB193372
HostMouse
IsotypeIgG1
ReactivityHuman
ApplicationIHC-P
ClonalityMonoclonal
Clone NumberCEA31
Concentration0.2 mg/mL Batch dependent concentration
ImmunogenCell preparation containing CEACAM5 protein. The exact immunogen used to generate this antibody is proprietary information.
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.05% Sodium azide Constituents: PBS, 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Cell surface glycoprotein that plays a role in cell adhesion, intracellular signaling and tumor progression (PubMed : 10864933, PubMed : 10910050, PubMed : 2803308). Mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6 (PubMed : 2803308). Plays a role as an oncogene by promoting tumor progression; induces resistance to anoikis of colorectal carcinoma cells (PubMed : 10910050).. (Microbial infection) Receptor for E.coli Dr adhesins. Binding of E.coli Dr adhesins leads to dissociation of the homodimer. See full target information CEACAM5

Category Paths

Request a product

Please provide the required information below so that we can quickly source your products.