Anti-CENPC antibody [2159C5a],Abcam,AB50974
Host
Mouse
Reactivity
Human
Application
WB, Dot
Platform ID
BAB447263355
Abcam
Contact
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Product Specifications
Scientific Background
Specifications
NameAnti-CENPC antibody [2159C5a]
Cat. No.AB50974
HostMouse
IsotypeIgG2b
ReactivityHuman
ApplicationWB, Dot
ClonalityMonoclonal
Clone Number2159C5a
Concentration0.1 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human CENPC aa 650-800. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein G
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.05% Sodium azide Constituents: PBS, 1% BSA
Storage-20°C
Regulatory StatusResearch Use Only
Scientific Background
Target data Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. CENPC recruits DNA methylation and DNMT3B to both centromeric and pericentromeric satellite repeats and regulates the histone code in these regions. See full target information CENPC
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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