Anti-CEP350 antibody [CL3423],Abcam,AB219831

Host

Mouse

Reactivity

Human

Application

ICC/IF, IHC-P

Platform ID

BAB822550717

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-CEP350 antibody [CL3423]
Cat. No.AB219831
HostMouse
IsotypeIgG1
ReactivityHuman
ApplicationICC/IF, IHC-P
ClonalityMonoclonal
Clone NumberCL3423
Concentration0.5 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human CEP350 aa 1400-1550. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine)
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Plays an essential role in centriole growth by stabilizing a procentriolar seed composed of at least, SASS6 and CENPJ (PubMed : 19052644). Required for anchoring microtubules to the centrosomes and for the integrity of the microtubule network (PubMed : 16314388, PubMed : 17878239, PubMed : 28659385). Recruits PPARA to discrete subcellular compartments and thereby modulates PPARA activity (PubMed : 15615782). Required for ciliation (PubMed : 28659385). See full target information CEP350

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